婴幼儿2019冠状病毒病的临床特点及胸部CT表现
作者:
作者单位:

作者简介:

王立非,男,主任医师。Email:wanglf007n@163.com。

通讯作者:

中图分类号:

基金项目:


Clinical features and chest CT findings of coronavirus disease 2019 in infants and young children
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的 探讨婴幼儿2019冠状病毒病(COVID-19)的临床特点及胸部CT表现。方法 收集并回顾性分析2020年1月20日至2月10日经核酸检测确诊为COVID-19的婴幼儿(0~3岁)患者的临床资料及胸部CT资料。结果 9例患儿均有流行病学史,呈家庭聚集性发病。9例患儿中无症状5例,发热4例,咳嗽2例,流涕1例,均无呼吸系统以外症状。9例患儿实验室检查均未见白细胞及淋巴细胞计数减少,其中6例淋巴细胞计数升高及2例白细胞计数升高。9例患儿中8例CT显示肺部炎症,病灶均位于胸膜下或叶间裂下,3例病灶同时沿支气管血管束分布;病灶形态以结节状(6例)及小斑片状(7例)为主;6例病灶呈磨玻璃影及实变影共存,其中3例可见"晕征",未见典型"铺路石征"。结论 婴幼儿COVID-19患者临床症状轻,影像学表现不如成人典型,其诊断需结合流行病学史及核酸检测综合判断,胸部CT对于无症状患儿的早期诊断有指导意义。

    Abstract:

    Objective To study the clinical features and chest CT findings of coronavirus disease 2019 (COVID-19) in infants and young children. Methods A retrospective analysis was performed for the clinical data and chest CT images of 9 children, aged 0 to 3 years, who were diagnosed with COVID-19 by nucleic acid detection between January 20 and February 10, 2020. Results All 9 children had an epidemiological history, and family clustering was observed for all infected children. Among the 9 children with COVID-19, 5 had no symptoms, 4 had fever, 2 had cough, and 1 had rhinorrhea. There were only symptoms of the respiratory system. Laboratory examination showed no reductions in leukocyte or lymphocyte count. Among the 9 children, 6 had an increase in lymphocyte count and 2 had an increase in leukocyte count. CT examination showed that among the 9 children, 8 had pulmonary inflammation located below the pleura or near the interlobar fissure and 3 had lesions distributed along the bronchovascular bundles. As for the morphology of the lesions, 6 had nodular lesions and 7 had patchy lesions; ground glass opacity with consolidation was observed in 6 children, among whom 3 had halo sign, and there was no typical paving stone sign. Conclusions Infants and young children with COVID-19 tend to have mild clinical symptoms and imaging findings not as typical as those of adults, and therefore, the diagnosis of COVID-19 should be made based on imaging findings along with epidemiological history and nucleic acid detection. Chest CT has guiding significance for the early diagnosis of asymptomatic children.

    参考文献
    相似文献
    引证文献
引用本文

周昀, 杨根东, 冯凯, 黄华, 云永兴, 牟薪砚, 王立非.婴幼儿2019冠状病毒病的临床特点及胸部CT表现[J].中国当代儿科杂志,2020,22(3):215-220

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2020-02-22
  • 最后修改日期:2020-02-27
  • 录用日期:
  • 在线发布日期: 2020-03-25
  • 出版日期:
您是第位访问者
ICP:湘ICP备17021739号-4
中国当代儿科杂志 ® 2024 版权所有
技术支持:北京勤云科技发展有限公司