石家庄市儿童Ⅰ型糖尿病发病率调查

Incidence of Type Ⅰ Diabetes Mellitus in Children in Shijiazhuang

摘要:

目的 了解石家庄市儿童I型糖尿病(IDDM)发病情况。方法 对石家庄市(包括郊县)1985～1997年间新发病的0～14岁的IDDM患者进行了回顾性调查。所有病例均来自医院、中小学及幼儿园。结果 共调查出51例，男23例，女28例。1985～1997年平均年粗发病率为0.60/10万，95%可信限(CI): 0.44～0.77，调整率为0.64/10万，95% CI: 0.35～0.93，校正率为0.71/10万，95% CI: 0.53～0.88。1985年为发病高峰，春秋季节发病较多，10～14岁组发病率高于0～4岁及5～9岁组。其中又以4岁和14岁为发病高峰,男女发病率无显著差异。结论 儿童Ⅰ型糖尿病的发病率与年龄组及季节有关。

Abstract:

Objective To report the incidence of type Ⅰ diabetes mellitus (IDDM) of children in Shijiazhuang. Methods A retrospective study was carried out in children (aged 0～14 years) with IDDM at onset in Shijiazhuang during 1985～1997. Cases were collected from hospitals (primary source), primary schools, middle schools, and kindergartens (secon d source). Results We found 51 children (23 boys, 28 girls) wit h type I diabetes mellitus. The average crude annual incidence rate was 0.60 per 100 000 (95% CI: 0.44～0.77), adjusted annual incidence rate was 0.64 per 100 000 (95% CI: 0.35～0.93) and ascertainment corrected incidenc e rate was 0.71 per 100 000 (95% CI: 0.53～0.88). In 1985 there was a incidence peak, and the incidence was particularly high in spring and autumn . The incidence rate was higher in the 10～14-year group than in other groups (0 ～4-year group and 5～9-year group) and the peak incidence fell at 4 years and 1 4 years. There was no significant difference in boys and girls. Conclusi ons The onset of IDDM in children appears to be relative to children's age and the specific season.