儿童不同类型慢性胃炎液体相胃排空的探讨

Liquid Gastric Emptying in Children with Chronic Gastritis

摘要:

目的 探讨液体相胃排空功能与胃镜下不同表现的儿童慢性胃炎的关系及其临床意义。方法：根据胃镜下粘膜损伤表现将儿童慢性胃炎分为单纯充血水肿型(CEG)、伴球部糜烂型(GDBE)和伴胆汁返流型(GBR)，采用胃窦体积法实时超声显像观察3型的液体相胃排空时间并分别与正常对照组比较。结果：CEG型和GBR型胃排空时间［(92.0±10.1)，(120.6±13.6) min］均较正常对照组［(52.8±8.3) min］显著延长(P<0.01)；而GDBE型［(59.2±11.9) min］与正常对照组比较差异无显著性(P> 0.05)。结论：儿童慢性胃炎液体相胃排空存在不一致现象且与胃镜下表现相关。测定液体相胃排空对于指导临床用药、判断疗效具有实际意义。

Abstract:

OBJECTIVE: To study the relationship between liquid gastric emptying time and different types of chronic gastritis in children. METHODS: Sixty one cases of chronic gastritis were diagnosed by the gastroscope and they were divided into three types according to the pathologic changes under the gastroscope: simple congestive edema gastritis (CEG), gastritis companying duodenal bulb erosion (GDBE) and gastritis companying bile reflux (GBR). Fifteen children who had no pathologic changes under the gastroscope were used as the controls. Liquid emptying time was detected with real time ultrasonography. RESULTS: Except in GDBE, gastric emptying time in CEG [( 92.0 ± 10.1 ) min] and GBR [( 120.6 ± 13.6 ) min] was remarkably prolonged compared with the normal controls [( 52.8 ± 8.3 ) min](P< 0.01 ). CONCLUSIONS: Liquid gastritis emptying time in children with chronic gastritis is correlated to the pathologic changes under the gastroscope. Determining liquid gastritis emptying time might be useful in selecting drugs and estimating curative effects in the treatment of different types of chronic gastritis.