807例住院儿童弓形虫感染调查分析

Toxoplasma Infectionin in 807 Inpatient Children

摘要:

目的：研究该院住院儿童弓形虫感染情况，探讨防治方法。方法：使用统一调查表问卷调查，同时采集静脉血807份，以ELISA法检测血清弓形虫IgG和IgM。结果：弓形虫IgG阳性率为3.28%，IgM为1.98%。除新生儿组外，婴儿组、幼儿组、学龄前期组、学龄期、青少年组弓形虫IgG，IgM阳性率随年龄递增而有升高趋势。有猫狗接触史组弓形虫IgG阳性率高于无猫狗接触组(6.01% vs2.40%)，差异有显著性(P<0.05)。不吃羊肉串、火锅、切菜板生熟分开组弓形虫IgG阳性率2.79%，IgM阳性率1.06%，低于有不良饮食习惯组(9.43%，15.09%)，两组比较差异有显著性意义(P<0.01)。结论：应加强健康教育，养成良好的生活习惯及饮食习惯，以减少弓形虫感染。

Abstract:

OBJECTIVE: To study the features of toxoplasmosis in children in order to develop effective treatment and prophylaxis regimens.METHODS: The levels of IgG and IgM of toxoplasma gondii were measured using ELISA in 807 inpatient children. Meanwhile, the subjects' living habits and dietary habits were studied. RESULTS: Of the 807 cases, the positive rates of IgG and IgM of toxoplasma gondii were 3.22% and 1.98% respectively; the titres rose with age in all the subjects except for neonates. The positive rate of toxoplasma gondii IgG in children who had contact with cats or dogs was higer than that in children who had not contact with cats or dogs ( 6.01% vs 2.04% ), P< 0.05 . The positive rates of toxoplasma gondii IgG and IgM in those who did not consume half cooked mutton and chafing dish food and did not share the same chopping board for cooked and half cooked food were lower than those of children who had bad living and dietary habits ( 2.78% vs 9.43% , 1.06% vs 15.09% ), P< 0.01 . CONCLUSIONS: It is important to emphasize health education and to develop good living habits and dietary habits in order to eradicate toxoplasmosis.