早产儿血脂水平与出生体重的关系

Relationship Between Blood Lipid Level and Birth Weight in Preterm Infants

摘要:

目的：过检测血脂探讨早产儿血脂水平与早产儿出生体重的关系。方法：50例早产儿在出生后即取标本检测血脂，测量体重；同期检测30例足月正常新生儿的血脂作对照。结果：与足月儿比较，早产儿总血清胆固醇(TCHO)、甘油三脂(TG)、低密度脂蛋白(LDL)、载脂蛋白A1(ApoA1)和载脂蛋白B(ApoB)水平均较低，差异有显著性(P<0.05)。其中低体重儿组与极低体重儿组比较，TCHO，TG，LDL，ApoA1和ApoB水平均较高，差异有显著性(P<0.05)。早产儿体重与总血清胆固醇(TCHO)呈显著正相关(r=0.463，P<0.01)；早产儿体重与甘油三脂(TG)呈显著正相关(r=0.284，P<0.05)。结论：早产儿血脂代谢水平反映婴儿的营养状态，血脂水平与出生体重呈正相关。

Abstract:

OBJECTIVE: To study the relationship between blood lipid level and birth weight in preterm infants and to provide guidelines for nutritional support for pretem infants. METHODS: The blood lipid level and birth weight were measured in 50 preterm infants and 30 full term infants. RESULTS: The levels of total cholesterol (T CHO), triglyceride (TG), low density lipoprotein (LDL), apolipoprotein A 1 (APO A 1) and apolipoprotein B (Apo B) in the preterm infants were significantly lower than those in the full term infants (P< 0.05 ); the levels of T CHO, TG, LDH, ApoA 1 and ApoB in the low birth weight infants were higher than those in the very low birth weight infants (P< 0.05 ). The levels of T HCO and TG were positively correlated to birth weight in the preterm infants (r= 0.463 , P< 0.01 ; r= 0.284 , P< 0.05 ; respectively). CONCLUSIONS: The blood lipid level may be a marker of the nutritional state in preterm infants. There is a positive correlation between the blood lipid level and birth weight in preterm infants.