妊娠期糖耐量降低对新生儿的影响

Effect of Gestational Impaired Glucose Tolerance on the Newborns

摘要:

目的：探讨妊娠期糖耐量降低(GIGT)对新生儿的影响。方法：对GIGT孕妇52例(GIGT组)、正常孕妇40例(对照组)的新生儿进行比较。结果：GIGT组巨大儿发生率明显高于对照组(21.2%vs 5.0%)，(P<0.05)，生后2 h血糖均值低于对照组［(1.52±0.66) mmol/Lvs(2.58±0.57) mmol/L］(P<0.01)，低血糖、高胆红素血症、红细胞增多症等并发症发病率高于对照组，但差异无显著性。结论：GIGT对新生儿的预后有一定影响，应引起重视。

Abstract:

OBJECTIVE: To study the effect of gestational impaired glucose tolerance (GIGT) on the newborns. METHODS: Fifty two newborns born to women with GIGT (GIGT group) and 40 newborns (gestational age matched) born to normal women (control group) were recruited in this study. RESULTS:The incidence of macrosomia in the GIGT group was obviously higher than that of the control group ( 21.2% vs 5.0% ; P< 0.05 ). The blood glucose level in the GIGT group at 2 h of life was significantly lower than that of the control group [( 1.52 ± 0.66 ) mmol/L vs ( 2.58 ± 0.57 ) mmol/L; P< 0.01 ]. Although the incidences of hypoglycemia, hyperbilirubinemia and polycythemia were higher than those of the control group, no statistical difference was noted. CONCLUSIONS: GIGT may have adverse effects on the newborns