早产儿脑性瘫痪婴儿期症状临床流行病学研究

Epidemiologic Study of Infancy Symptoms of Cerebral Palsy in Premature Birth Children

摘要:

目的：了解小儿脑性瘫痪婴儿期症状，为儿科医生、儿保医生提供脑瘫的早期筛查、早期诊断线索。方法：对江苏省7县市1～6岁4167例早产儿脑瘫患病率、脑瘫婴儿期症状进行调查，由受过统一培训的儿科医生、儿保医生完成。结果：早产儿脑瘫患病率为 32.9‰，胎龄小于32周的早产儿脑 瘫患病率为34～37周早产儿的3.6倍。脑瘫症状婴儿期的检出率在30%～62%之间，特异度在99.4%以上，准确度在97.2%以上。阳性预测值在80%以上，阴性预测值在97.5%以上。结论：脑瘫婴儿期症状为早产儿脑瘫的早期诊断提供了依据，适用于脑瘫的早期筛查和早期诊断。

Abstract:

OBJECTIVE: To study the infancy symptoms of premature birth children with cerebral palsy so as to provide a criterion for early screening and diagnosis of cerebral palsy.METHODS: The incidence of cerebral palsy and its infancy symptoms were investigated in 4 167 pre term birth children ranging from 1-6 years old from 7 counties/cities of Jiangsu Province. Pediatricians and health care doctors finished the investigation.RESULTS: The average incidence of cerebral palsy in pre term birth children was 32.9‰ . The incidence of cerebral palsy in pre term birth children with the gestational age of less than 32 weeks was 3.6 times as much as that in ones with the gestational age of 34-37 weeks. The positive rate of infancy symptoms of cerebral palsy was 30%-62%, with the specificity over 99.4% and veracity over 97.2% . The positive expected value was over 80%, and negative one was over 97.5% . CONCLUSIONS: The infancy symptoms of cerebral palsy can be used for early screening and diagnosis for cerebral palsy in premature birth children.