1 500例遗尿症的功能性膀胱容量分析

Functional bladder capacity in 1 500 children with nocturnal enuresis

摘要:

目的：分析了解遗尿症患儿的功能性膀胱容量（FBC）及其与尿床次数的相关性，为遗尿症的治疗提供临床依据。方法：对1 500例遗尿症患儿进行问卷调查及泌尿系B超检查，尤其是功能性膀胱容量的测定。结果：①男∶女=1.3∶1，5~10岁：1 305例（87%）；10~14岁：181例（12%）；15~18岁：14例（1%）。②FBC≤正常值的50％（即FBC减少）的尿床患儿共637例（42.4％）。③1 500例患儿中，按尿床程度分为4组：尿床≥2次/每晚的患儿53例（3.5%）；尿床次数≥7次/周的患儿969例（64.6%）；尿床3~6次/周的患儿380例（25.3%）；尿床1~2次/周的患儿98例（6.5%）；其FBC减少的发生率分别是79.2％，48.3％，29.7％和14.3％，组间比较差异有显著性。结论：在深圳地区就诊的遗尿患儿大多数为每天尿床的重型遗尿症，其中近一半的患儿存在着功能性膀胱容量减少，并且与尿床的程度具有高度的相关性，尿床次数越频繁，FBC减少的比例越高。

Abstract:

OBJECTIVE: To study the association of functional bladder capacity with the severity of bedwetting in children with nocturnal enuresis. METHODS: A questionnaire investigation was performed in 1 500 children with nocturnal enuresis and the functional bladder capacity was examined by B-ultrasound. RESULTS: The ratio of males to females was 1.3:1. The majority of patients (87%)were in an age range of 5-10 years, followed by the 10-14 years group (12%), and the 15-18 years group (1%). Six hundred and thirty-seven patients (42.4%) showed a decreased functional bladder capacity (less than 50% of normal level). The patients were classified into four groups according to the severity of bedwetting (from severe to mild): ≥2 times per night (n=53, 3.5%), ≥7 times per week (n=969, 64.6%), 3-6 times per week (n=380, 25.3%) and 1-2 times per week (n=98, 6.5%). The incidence of the reduction in functional bladder capacity in the above four groups was 79.2%, 48.3%, 29.7% and 14.3% respectively and a significant difference was noted among the four groups. CONCLUSIONS: Most of children with nocturnal enuresis showed decreased functional bladder capacity. Functional bladder capacity is associated with the severity of bedwetting in children with nocturnal enuresis.