心肌矢量应变评价川崎病患儿左心局部收缩功能

Assessment of regional left ventricular systolic function by VSI in children with Kawasaki disease

摘要:

目的：应用心肌矢量应变力和应变率成像技术（VSI）对川崎病患儿治疗前后左心室局部收缩功能进行研究。方法：VSI技术检测32例川崎病患儿治疗前及治疗后1个月及30例年龄匹配的正常儿童左心室局部收缩功能。结果：①纵向应变率收缩期峰值（LSRs）比较：治疗前左心室9个节段LSRs值低于正常对照组；治疗后6个节段LSRs值低于正常对照组，9个节段LSRs值高于治疗前。②径向应变率收缩期峰值（RSRs）比较：治疗前8个节段RSRs值较正常对照组减低；治疗后1个节段的RSRs值低于正常对照组，5个节段RSRs值高于治疗前。③圆周方向运动速度收缩期峰值（CVs）比较：治疗前6个节段CVs值低于正常对照组；治疗后1个节段低于正常对照组；3个节段CVs值高于治疗前。结论：VSI技术能够准确、全面地评估川崎病患儿治疗前、后左室局部收缩功能，对川崎病的治疗有重要临床指导意义。［中国当代儿科杂志，2010，12（4）：248-251］

Abstract:

OBJECTIVE: To assess the regional left ventricular systolic function of children with Kawasaki disease before and after treatment by vector myocardial strain and strain rate imaging (VSI) technology. METHODS: The regional left ventricular systolic function was assessed using VSI technology in 32 children with Kawasaki disease before treatment and one month after treatment and in 30 age-matched normal children. RESULTS: Nine segments of the left ventricular in the Kawasaki disease group before treatment had decreased longitudinal peak systolic strain rate (LSRs) compared with the normal control group. After treatment, the LSRs in 9 segments in the Kawasaki disease group increased, but 6 segments had decreased LSRs compared with the normal control group. The radial peak systolic strain rate (RSRs) of 8 segments in the Kawasaki disease group before treatment was lower than that in the control group. After treatment, only one segment had decreased RSRs compared with the control normal group and 5 segments had increased RSRs compared with that before treatment. The circumferential peak systolic velocity (CVs) of 6 segments in the Kawasaki disease group before treatment group was lower than that in the control normal group. After treatment, only one segment had decreased CVs in the Kawasaki disease group compared with the control normal group and 3 segments had increased CVs compared with that before treatment. CONCLUSIONS: The regional left ventricular systolic function in children with Kawasaki disease before and after treatment can be accurately assessed using VSI technology, which shows the clinical significance of this technology in assessment of treatment outcome in children with Kawasaki disease.［Chin J Contemp Pediatr, 2010, 12 (4):248-251］