特应性皮炎儿童生活质量调查

Quality of life in children with atopic dermatitis

摘要:

目的：特应性皮炎常造成儿童行为、情感、心理发育等方面的异常。本研究旨在调查特应性皮炎幼儿的生活质量。方法：应用儿童特应性皮炎影响量表 (Childhood Atopic Dermatitis Impact Scale，CADIS)调查问卷进行生活质量调查, 并用特应性皮炎评分量表(SCORing Atopic Dermatitis，SCOARD)对特应性皮炎患儿进行临床症状评估。结果：患儿SCORAD评分为56.9±11.1；CADIS评分为38.0±7.9。CADIS与SCORAD存在显著正相关(ρ=0.934,P＜0.05), 其中,与受累面积(ρ=0.581,P＜0.01)、红斑(ρ=0.417,P＜0.01)、糜烂(ρ=0.579,P＜0.01)、水肿丘疹(ρ=0.595,P＜0.01)、渗出结痂(ρ=0.436,P＜0.01)、皮肤干燥(ρ=0.343,P＜0.01)、瘙痒和睡眠减少(ρ=0.0.344,P＜0.05)关系密切。结论：特应性皮炎对患儿生活质量有显著影响, 随着疾病严重程度升高,生活质量逐渐下降。［中国当代儿科杂志，2010，12（5）：351-353］

Abstract:

OBJECTIVE: Atopic dermatitis affects children’s behavioral, emotional and psychological development. This study aimed to investigate the quality of life in infants with atopic dermatitis. METHODS: The quality of life in 43 children with atopic dermatitis between the age of 3-6 months was assessed by the Childhood Atopic Dermatitis Impact Scale (CADIS). The severity of atopic dermatitis was determined by the SCORing Atopic Dermatitis (SCOARD). RESULTS: The scores of SCORAD and CADIS in children with atopic dermatitis were 56.9±11.1 and 38.0±7.9 respectively. There was a positive correlation between the CADIS and SCORAD scores (ρ=0.934, P<0.05). The CADIS score was positively correlated with the area of skin lesions (ρ=0.581, P<0.01), erythema (ρ=0.417, P<0.01), excoriations (ρ=0.579, P<0.01), edema/exanthema papulosum (ρ=0.595, P<0.01), oozing/crusts (ρ=0.436, P<0.01), skin dryness (ρ=0.343, P<0.01), pruritus and sleeplessness (ρ=0.0.344, P<0.05). CONCLUSIONS: Atopic dermatitis adversely affects the quality of life in children with atopic dermatitis. The worse quality of life is associated with more severe atopic dermatitis.［Chin J Contemp Pediatr, 2010, 12 (5):351-353］