男性儿童乳房发育38例临床分析

Gynecomastia in 38 children: etiology and treatment

摘要:

目的：对男性儿童乳房发育症的病因、治疗经验进行总结。方法：回顾性分析38例2~14岁男性儿童乳房发育症的临床资料。结果：38例中17例为男性青春期乳腺增生症，2例可能与原发疾病有关，4例因误服药物或接触含“性激素”类护肤品所致，15例为男性儿童特发性乳房发育症。对3例B3期男性乳房发育患儿给予乳癖消片1.34 g口服，每日3次，连服1月；对16例年龄≥12岁的B2期伴有明显症状的男性乳房发育患儿给予乳癖消片1.34 g口服，每日3次，连服3~5 d；其余均未给予药物治疗，仅针对原发病因治疗。随访1月至1年，绝大多数病例增大的乳房均消退。结论：导致男性儿童乳房发育症的原因包括青春期乳腺增生、误服药物以及其他疾病的合并症等。绝大多数男性儿童乳房发育症是生理性的，仅临床症状明显患儿予药物治疗。

Abstract:

OBJECTIVE: To summarize the etiology and treatment of gynecomastia in male children. METHODS: The clinical data of 38 boys with gynecomastia at ages of 2-14 years were retrospectively studied. RESULTS: In the 38 cases, 17 cases were identified as adolescent breast hyperplasia, 2 cases were relevant to primary disease, 4 cases were caused by ingestion of drugs containing hormone, and 15 cases did not show identifiable causes and were diagnosed as idiopathic gynecomastia. For the 3 children with breast development in B3 stage, oral rupixiao was administered (1.34 g, tid) for one month. For 16 children at ages of over 12 years with breast development in B2 stage and with obvious clinical symptoms, oral rupixiao was administered (1.34 g, tid) for 3-5 days. The other patients did not receive drug treatment. In a one month to one year follow-up, most of the patients recovered well. CONCLUSIONS: The etiology of gynecomastia in male children includes adolescent breast hyperplasia, ingestion of drugs containing hormone and secondary causes. Most gynecomastia can be attributed to physiological reasons. Only a few children with obvious clinical symptoms need drug treatment.［Chin J Contemp Pediatr, 2010, 12 (6):433-435］