儿童症状性癫癎手术疗效及影响因素的分析

Surgical outcomes of pediatric symptomatic epilepsy and their influencing factors

摘要:

目的：了解儿童症状性癫癎手术疗效的影响因素。方法：对从2004年10月至2008年9月经手术治疗的儿童症状性癫癎48例随访结果进行回顾性分析。结果：48例患儿中，43例获得随访，随访时间12～51个月，平均27.3月。患儿术后癫癎结果评价采用Engel标准，其中I级32例（74％），II级4例（9％），III级4例（9％），IV级3例（7％）。术前癫癎发作频率是癫癎手术预后的独立因素(P<0.05)。结论：儿童症状性癫癎手术疗效良好，术前癫癎发作频次是影响手术预后的因素。［中国当代儿科杂志，2010，12（9）：709-711］

Abstract:

OBJECTIVE: To investigate the surgical outcomes of pediatric symptomatic epilepsy and the influencing factors for postoperative outcomes. METHODS: A cohort of 48 children with symptomatic epilepsy received surgical treatment from October 2004 to September 2008. The surgical outcomes were followed up. RESULTS: A 27.3 months (range 12-51 months) follow-up was performed in 43 cases. Engel classification for evaluating postoperative epileptic outcomes showed that class I in 32 cases (74％), class II in 4 cases (9％), class III in 4 cases (9％) and class IV in 3 cases (7%). Preoperative seizure frequency is an independent predictor of postoperative epileptic outcomes (P<0.05). CONCLUSIONS: Operative treatment can lead to a favorable result in children with symptomatic epilepsy. Preoperative seizure frequency is an independent influencing factor for postoperative outcomes.［Chin J Contemp Pediatr, 2010, 12 (9):709-711］