节段性肺炎支原体肺炎患儿肺功能检测的临床意义

Pulmonary functions in children with segmental Mycoplasma pneumoniae pneumonia

摘要:

目的：探讨节段性肺炎支原体肺炎（SMPP）患儿肺功能变化及临床意义。方法：分别测定55例SMPP患儿急性期和恢复期的肺功能，包括FVC、FEV1、FEV1/FVC、PEF、FEF25%、FEF50%、FEF75%、FEF25%-75%。结果55例SMPP患儿急性期FVC、FEV1、FEV1/FVC、PEF、FEF25%、FEF50%、FEF75%及FEF25%-75%均有不同程度降低，以FEF25%、FEF50%、FEF75%和FEF25%-75%降低较为明显。恢复期各项指标均有明显改善，两组比较差异有统计学意义（P<0.05）。多部位病变SMPP患儿急性期FVC和FEV1较单个叶段病变患儿下降明显（P<0.05）。结论 SMPP患儿急性期大、小气道功能均有不同程度损伤，多表现为限制性通气障碍，小气道功能受损更明显；恢复期肺功能明显好转。多叶段病变大气道功能受损较单个叶段病变严重。

Abstract:

OBJECTIVE: To investigate the changes of pulmonary functions in children with segmental Mycoplasma pneumoniae pneumonia (SMPP). METHODS: A total of 55 children with SMPP were recruited into this study. Pulmonary functions were measured at both acute and recovery phases, including FVC, FEV1, FEV1/FVC, PEF, FEF25%, FEF50%, FEF75% and FEF25%-75%. RESULTS: FVC, FEV1, FEV1 /FVC, PEF, FEF25%, FEF50%, FEF75%, and FEF25%-75% were reduced in all of the 55 cases at the acute phase. FEF25%, FEF50%, FEF75% and FEF25%-75% decreased more significantly. The indexes above mentioned were improved significantly at the recovery phase compared with the acute phase (P<0.05). During the acute phase FVC and FEV1 decreased more significantly in the group with multiple area lesions than in the group with single area lesions (P<0.05). CONCLUSIONS: Both large and small airway functions are damaged in different degrees in children with SMPP during the acute phase. More cases show restrictive ventilatory disorders and the injury of small airway function is more severe. The pulmonary function is markedly improved at the recovery phase, suggesting that the pulmonary function impairments are reversible. The pulmonary function impairments are more severe in children with multiple area lesions.