儿童胃食管反流的食管外症状研究进展

Advances in research on extra-oesophageal symptoms of pediatric gastroesophageal reflux

摘要:

儿童胃食管反流（GER）临床表现复杂多样，食管外症状是其重要的表现形式，包括与反流相关的呼吸道疾病、耳鼻咽喉部疾病、口腔疾病及神经精神症状等，其因果关系尚未能完全阐明。本文主要描述了GER与哮喘、慢性咳嗽、咽喉炎、喉乳头状瘤、鼻炎鼻窦炎、分泌性中耳炎、牙酸蚀症、明显生命危险事件、婴儿哭吵综合征等关系的研究进展，为儿童GER相关疾病的诊断和治疗提供新的思路。

Abstract:

The manifestations of pediatric gastroesohageal reflux (GER) are varied and complex. Extra-oesophageal symptoms, including GER-related respiratory diseases, ear, nose and throat diseases, oral diseases and neuropsychiatric symptoms, are thought to be major manifestations of pediatric GER, but the causal relationship between GER and these extra-oesophageal symptoms is still unclear. Therefore, we describe the progress of reseach on the relationship between GER and asthma, chronic cough, laryngitis, pharyngitis, laryngeal papilloma, sinusitis, otitis media, dental erosion, apparent life-threatening event, and the crying baby syndrome in this review. It provides new strategies for the diagnosis and treatment of GER-related diseases in children.