晚期早产儿体格生长的前瞻性研究
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R722.6

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A prospective study of late preterm infants' physical growth
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    目的:评价不同胎龄晚期早产儿(late preterm infants, LPI)的出生体重(birth weight, BW)和矫正胎龄(correct age, CA)1、3、6月龄时的体格生长情况,为早产儿长期体格生长随访提供监测重点。方法:收集2010年5月至2011年9月就诊的287例LPI相关资料,评价LPI的BW和其在CA 1、3、6月龄时的体格生长情况。结果:(1)287例LPI中,胎龄34~34+6周和35~35+6周LPI平均BW低于1986年中国15城市不同胎龄新生儿参考值(P<0.05);胎龄36~36+6周单胎LPI(128例)平均BW高于1986年中国15城市不同胎龄新生儿参考值(P<0.05)。(2)在CA 1、3、6月时,90%以上LPI的各项生长指标达到或超过P3水平。CA 1、3月龄时,年龄别体重和头围明显大于2005年我国九市城区7岁以下正常儿童参考值(P<0.05)。(3)各CA的年龄别身长与参考值差异均无统计学意义。结论:与1986年中国15城市不同胎龄新生儿BW值比较,LPI的BW有变化,提示我国不同胎龄新生儿BW标准需间隔一定时间后重新调查制定。LPI 在CA 6月龄前存在超重的危险,需要更长期的监测。LPI的身长的生长应作为今后LPI生长随访监测的重点。

    Abstract:

    OBJECTIVE: To evaluate birth weights (BW) in late preterm infants (LPI) with different gestational ages (GA) and their physical growths at correct ages (CA) 1, 3 and 6 months. METHODS: A total of 287 LPIs were recruited for a cohort study between May 2010 and September 2011. Birth weights (BW) in infants with different gestational ages and their physical growths at CA 1, 3 and 6 months were evaluated. RESULTS: Of the 287 LPIs, mean BW in LPIs with gestational ages of 34-34+6and 35-35+6weeks was significantly lower than the reference value from a physical growth investigation on newborns of 15 cities of China in 1986 (P<0.05). However, mean BW in singleton LPIs (n=128) with gestational ages of 36-36+6weeks was significantly higher than the reference value (P<0.05). At CA 1, 3 and 6 months, more than 90% LPIs reached P3 level in weights for age, length for age and head circumference for age. At CA 1 and 3 months, weight for age and head circumference for age in the LPIs were statistically higher than the reference values of physical growth in children under 7 years from nine cities of china in 2005 (P<0.05). Mean length for age at CA 1, 3 and 6 months was not significantly different from the reference value. CONCLUSIONS: There are obvious differences in BW in the LPIs compared with the reference value from a physical growth investigation on newborns of 15 cities of China in 1986, suggesting that the reference value of BW at different gestational ages needs to be updated in a certain interval. Before CA 6 months, there is a risk of overweight in LPIs and long-term monitoring is necessary. Growth of length should be followed-up for a long time.

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张站站,程茜.晚期早产儿体格生长的前瞻性研究[J].中国当代儿科杂志,2012,14(07):481-484

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  • 在线发布日期: 2012-07-15
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