热性惊厥与注意缺陷多动障碍关系探讨

Relationship between febrile convulsion and attention deficit hyperactivity disorder

摘要:

目的探讨热性惊厥（ＦＣ）与注意缺陷多动障碍（ＡＤＨＤ）的关系。方法由小儿神经专科医师对１７２例ＦＣ进行５～１０年远期随访，Ｃｏｎｎｅｒ’ｓ简明症状问卷等方法对患儿进行测试。结果有ＦＣ史小儿ＡＤＨＤ患病率为２３．８％（４１／１７２），与无ＦＣ史的小儿ＡＤＨＤ患病率５．１％（１４／２７３）相比，差异有非常显著性（Ｐ＜０．０１）。另外ＦＣ的发作次数＜４次和≥４次，持续时间＜３０ｍｉｎ和≥３０ｍｉｎＡＤＨＤ患病率相比均有非常显著差异（Ｐ＜０．０１）。结论本资料提示ＦＣ多次、长时间发作可能是小儿ＡＤＨＤ发生原因之一，小儿反复性热性惊厥，有复发或癫痫危险因素宜用药物预防

Abstract:

Objective To study the relationship between febrile convulsion (FC) and attention deficit hyperactivity disorder (ADHD).Methods One hundred and seventy-two children with FC were examined using Conner's abbreviated symptom questionnaire by neurological pediatrician and followed-up for 5 to 10 years.Results There were 41 cases of ADHD in 172 cases of FC. The morbidity of ADHD was significantly higher in the children with FC (23.8%, 41/172) than that children without FC (5.1%, 14/273), (P<0.01).The morbidity of ADHD was significantly higher in the FC children with fits frequency ≥4 and fits duration ≥30 min than those FC children with fits frequency <4 amd fits duration <30 min. Conclusions The results suggest that multiple and prolonged convulsion is one of causes of ADHD in children.Anticonvulsants and prophylaxis should be given to children with FC and with a risk of recurrence and epilepsy.