功能性构音障碍儿童的听觉事件相关电位研究

Auditory event-related potentials in children with functional articulation disorders

摘要:

目的：探讨功能性构音障碍（FAD）患儿中枢听觉加工特点及儿童FAD的可能病因。 方法：选择符合 FAD 诊断标准的 27 例患儿作为病例组, 年龄匹配的正常儿童 50 例作为对照组，比较病例组与对照组个人语言发育史阳性病史率，检测二组儿童事件相关电位，比较其失匹配负波（MMN）形态学、潜伏期及峰振幅。结果：病例组个人语言发育史中阳性病史比例显著高于对照组，差异有统计学意义（70% vs 8%，P<0.01）；其MMN峰潜伏期较对照组显著延长，差异有统计学意义（209±31 ms 175±32 ms，P<0.01）；其峰振幅低于对照组，但差异无统计学意义（P>0.05）。结论：中枢听觉加工时间延长可能是儿童FAD的发病原因之一。

Abstract:

OBJECTIVE: To investigate the central auditory processing function in children with functional articulation disorders (FAD), and possible causes of FAD. METODS: Twenty-seven children with FAD were selected as the case group and 50 age-matched normal children were selected as the control group. The two groups were compared with respect to the following factors: percentage of individuals with a positive history of language development disorder, and the form, peak latency and peak amplitude of mismatch negativity (MMN) on auditory event-related potentials. RESULTS: Compared with the control group, the case group had a significantly higher percentage of individuals with a positive history of language development disorder (70% vs 8%; P<0.01), a significantly prolonged peak latency of MMN (209±31 ms vs 175±32 ms; P<0.01), and an insignificantly lower peak amplitude of MMN (P>0.05). CONCLUSIONS: Prolonged central auditory processing may be one of the causes of FAD in children.