甲型H5N1和H7N9禽流感--关注2013年H7N9禽流感疫情

A(H5N1) and A(H7N9) avian influenza: the H7N9 avian influenza outbreak of 2013

摘要:

禽流感病毒可以感染人类，通常病情轻微，1997年出现的H5N1禽流感和本年初出现的H7N9禽流感病情严重，病死率高。青少年和儿童H5N1禽流感病死率低于成人，年龄越小，病死率越低。有限的儿童病例经治疗迅速康复，以及儿童携带者的发现提示儿童H7N9禽流感病情轻微。禽流感治疗强调尽早使用奥司他韦进行抗病毒治疗，重症者需积极的呼吸支持、循环支持和抑制免疫反应等综合治疗。

Abstract:

influenza virus can infect humans and cause disease. The clinical presentation of human infection is usually mild, but the infection caused by A(H5N1) avian influenza virus occurring initially in Hongkong in 1997 or the A(H7N9) virus isolated first at the beginning of this year in China is severe and characterized by high mortality. The mortality rate of adolescents and children caused by H5N1 avian influenza is lower than that of adults and the younger the child the lower the mortality rate. A few pediatric H7N9 avian influenza cases recovered soon after treatment. A child was determined to be a H7N9 avian influenza virus carrier. These findings suggested that the pediatric H7N9 avian influenza infection was mild. It is very important to start anti-virus treatment with oseltamivir as early as possible in cases of avian influenza infection is considered. Combined therapy, including respiratory and circulatory support and inhibiting immunological reaction, is emphasized in the treatment of severe cases.