儿童注意缺陷多动障碍家庭危险因素的Meta 分析
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孙桂香,女,副教授。gxsunny@hotmail.com

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江苏高校哲学社会科学研究基金项目(2012SJB190015)。


A Meta analysis of family risk factors for attention deficit hyperactivity disorder
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    摘要:

    目的 综合分析儿童注意缺陷多动障碍(ADHD)家庭危险因素,为今后防治工作提供依据。方法 系统收集2000~2014 年涉及中国儿童ADHD 发病危险因素的病例对照文献,从中提取家庭因素有关数据;按照NOS 标准对纳入文献进行质量评价;采用Stata 12.0 软件对纳入文献进行Meta 分析。结果 最终纳入16 篇文献,包括ADHD 病例2 167 例,对照2 148 例。Meta 分析显示,良好的教养方式(OR=0.32,95%CI:0.26~0.40)、核心家庭(OR=0.56,95%CI:0.41~0.76)、父亲文化程度高(OR=0.56,95%CI:0.41~0.76)、母亲文化程度高(OR=0.65,95%CI:0.47~0.89)、母亲性格外向(OR=0.33,95%CI:0.18~0.61)是儿童ADHD 的保护因素;父母关系差(OR=1.90,95%CI:1.17~3.06)和ADHD 家族史(OR=5.86,95%CI:3.67~9.35)是ADHD 的危险因素。结论 良好的教养方式、核心家庭类型、父母文化程度高以及母亲性格外向可降低儿童ADHD 的发病风险,而父母关系差、ADHD 家族史可增加ADHD 患病的风险。

    Abstract:

    Objective To investigate the risk factors for attention deficit hyperactivity disorder (ADHD) and to provide a basis for future prevention and treatment of this disease. Methods Following a systematic search for casecontrol studies on the risk factors for ADHD in China between 2000 and 2014, relevant family risk factors were extracted accordingly. The quality of selected studies was evaluated according to the NOS scale. A Meta analysis on the selected studies was conducted using Stata 12.0 software. Results A total of 16 studies were selected, involving 2 167 children with ADHD and 2 148 normal controls. Results of Meta analysis showed that good parenting (OR=0.32, 95% CI: 0.26-0.40), nuclear family (OR=0.56, 95% CI: 0.41-0.76), high education level of father (OR=0.56, 95% CI: 0.41-0.76), high education level of mother (OR=0.65, 95% CI: 0.47-0.89), and extroversion of mother (OR=0.33, 95% CI: 0.18-0.61) are favorable factors for ADHD. Poor parental relationship (OR=1.90, 95% CI: 1.17-3.06) and family history of ADHD (OR=5.86, 95% CI: 3.67-9.35) are risk factors for ADHD. Conclusions Good parenting, nuclear family, high education level of parents, and mother with extroversion are protective factors for ADHD, whereas poor parental relationship and family history of ADHD are associated with an increased risk for ADHD.

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张亚峰, 孙桂香.儿童注意缺陷多动障碍家庭危险因素的Meta 分析[J].中国当代儿科杂志,2015,17(7):721-725

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  • 收稿日期:2014-12-01
  • 最后修改日期:2015-01-17
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  • 在线发布日期: 2015-07-15
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