前白蛋白对重症坏死性小肠结肠炎的诊断价值

Diagnostic value of prealbumin for severe necrotizing enterocolitis

摘要:

目的 了解重症新生儿坏死性小肠结肠炎(NEC)的临床特点,探究前白蛋白(PA)对于重症NEC的诊断价值。方法 对40例NEC新生儿(Ⅱ期29例、Ⅱ期11例)的临床资料及血常规、血生化结果进行研究,采用多因素logistic回归分析以及ROC曲线判断PA在重症NEC诊断中的价值。结果 多因素logistic回归分析发现PA对于重症NEC(≥Ⅱ B期)的诊断具有参考价值。ROC曲线分析显示在重症NEC(≥Ⅱ B期)的诊断中,PA拥有较高的灵敏度(0.870)及特异度(0.647)。结论 PA对重症NEC(≥Ⅱ B期)具有较高的诊断价值。

Abstract:

Objective To study the clinical features of severe neonatal necrotizing enterocolitis(NEC), and to investigate the diagnostic value of prealbumin(PA) in neonates with severe NEC.Methods The clinical data and results of routine blood test and blood biochemical test of 40 neonates with NEC(29 neonates with NEC II and 11 with NEC III) were analyzed.The multivariate logistic regression analysis and receiver operating characteristic(ROC) curve were applied to investigate the value of PA in the diagnosis of severe NEC.Results The multivariate logistic regression analysis showed that PA was an important index for the diagnosis of severe NEC(≥IIB).The ROC analysis showed that in the diagnosis of severe NEC(≥IIB), PA had high sensitivity(0.870) and specificity(0.647).Conclusions PA has a good value in the diagnosis of severe NEC.