Abstract:Objective To study the clinical effect of maternal voice stimulation in alleviating procedural pain in neonates during heel blood collection. Methods A total of 72 neonates who were admitted to the neonate intensive care unit were randomly divided into an intervention group (n=35) and a control group (n=37). Heel blood collection was performed by the routine method in the control group. The intervention group listened to their mothers' voice from 1 minute before heel blood collection to the end of the procedure. Pain score, incidence of crying, and vital signs were recorded before and after heel blood collection. Results Compared with the control group, the heart rate was significantly reduced, the blood oxygen saturation significantly increased, the incidence of crying and the pain score were significantly reduced in the intervention group during the procedure of heel blood collection (P < 0.05). Conclusions Maternal voice stimulation helps to reduce procedural pain and maintain stable vital signs in neonates.