伊伐布雷定在儿童心血管疾病中的应用进展

Research progress in the application of ivabradine in children with cardiovascular diseases

摘要:

伊伐布雷定作为特异性I_f电流抑制剂，因其在降低心率的同时不影响心肌收缩力和血压，已广泛应用于成人慢性心力衰竭的治疗，并且在多种快速性心律失常中亦展现出良好的治疗效果。但伊伐布雷定在儿童心血管疾病的应用还有很多限制，该文就目前国内外关于伊伐布雷定治疗儿童心血管疾病的研究进展进行综述，以期为儿童心血管医生提供指导。

Abstract:

Ivabradine, as a specific I_f current inhibitor, has been widely used in the treatment of chronic heart failure in adults due to its ability to reduce heart rate without affecting myocardial contractility and blood pressure. It has also shown good effects in various types of tachyarrhythmias. However, the application of ivabradine in pediatric cardiovascular diseases still faces many limitations. This article reviews the current research progress on the use of ivabradine in treating pediatric cardiovascular diseases both domestically and internationally, aiming to provide guidance for pediatric cardiologists. Citation:Chinese Journal of Contemporary Pediatrics, 2024, 26(7): 782-788