儿童右肺中叶综合征的肺功能变化及其意义

Pulmonary function of children with right lung middle lobe syndrome

摘要:

目的：探讨右肺中叶综合征患儿治疗前后的肺功能变化及其临床意义。方法：将30例儿童右肺中叶综合征住院患儿分成两组，≤4岁组患儿20例选用2600型肺功能仪，>4岁组患儿10例选用MIR型肺功能仪，分别在治疗前和治疗后做肺功能测定，比较其治疗前后的肺功能参数的变化。2600型肺功能仪测定的主要参数取75%潮气量与最高呼气流速之比(25/PF)和潮气量与最高潮气呼气流速之比(%V-PF)2个参数来反映0~4岁组患儿的肺功能变化，MIR型肺功能仪测定的主要参数取最大肺活量(FVC)、1秒率(FEV1)和最高呼气流速(PEF)共3个参数来反映>4岁组患儿的肺功能变化。结果：≤4岁组治疗前肺功能参数的测定值分别为25/PF=0.42±0.08，%V-PF=0.28±0.03；治疗后的肺功能参数的测定值为25/PF=0.58±0.12，%V-PF=0.39±0.06。两者治疗前后比较差异有显著性，t=4.21，3.82；均P<0.05。>4岁组治疗前肺功能参数的测定值分别为FVC=1.75±0.32，FEV1=1.36±0.52, PEF=2.56±0.78；治疗后的肺功能参数的测定值分别为FVC=2.37±0.78，FEV1=2.08±0.65, PEF=3.68±0.80。治疗前后比较，分别t=3.05, 2.98，3.12；均P<0.05。结论：右肺中叶综合征患儿治疗前后的肺功能变化是明显的，治疗后肺功能可恢复正常。［中国当代儿科杂志，2009，11（8）：669-671］

Abstract:

OBJECTIVE: To study the changes of pulmonary function in children with right lung middle lobe syndrome before and after treatment. METHODS: Thirty children with right lung middle lobe syndrome were classified into two age groups: ≤4 years old and >4 years old. Pulmonary function was tested by the 2600-type and the MIR-type pulmonary function spirometry in the ≤4 years and the >4 years age groups, respectively before and after treatment. Terminal flows/peak expiratory flow (25/PF) and the percentage of tidal volume to peak tidal expiratory flow (% V-PF) were measured in the <4 years age group. Forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and peak expiratory flow (PEF) were measured in the >4 years age group. RESULTS: The values of 25/PF and %V-PF in the ≤4 years age group were 0.42±0.08 and 0.28±0.03, respectively before treatment. The values were improved after treatment (0.58±0.12 and 0.39±0.06 respectively) (P<0.05). The values of FVC, FEV1 and PEF were 1.75±0.32, 1.36±0.52 and 2.56±0.78, respectively in the >4 years age group before treatment. The values were also improved after treatment (2.37±0.78, 2.08±0.65 and 3.68±0.80 respectively) (P<0.05). CONCLUSIONS: There are significant differences in the pulmonary function before and after treatment in children with right lung middle lobe syndrome. The pulmonary function can return to normal after treatment.［Chin J Contemp Pediatr, 2009, 11 (8):669-671］