A serologic observation on chlamydia pneumoniae infection in children in Nanning area

Abstract:

Objective To understand the status of chlamydia pneumoniae (CP) infection in children with or without respiratary tract infection in Nanning area. Methods The specific serum IgG, IgM antibodies against CP were detected in 149 children with acute respiratory disease and in 111 control cases (55 with non-respiratory disorders and 56 healthy children). Results The positive IgG was 26% in children with acute respiratory disease and 12% in control children (P<0.01). The total positive rate of the specific serum IgG was 20%. The positive IgG rates in groups at age <3, 3～, 6～, and 12～15 years were 16%, 15%, 24%, and 43%, respectively. Twenty-four of the 149 patients (16%) had acute CP infection. Conclusions CP infection is widely present in all age groups of children in Nanning area and the infection rate increases with age.