Research advances in the pathogenesis of familial Kawasaki disease

Abstract:

Kawasaki disease has become the leading cause of acquired heart disease in children in North America and Japan. The incidence rate of Kawasaki disease varies signifcantly across regions and races. The frst-degree relatives of patients with Kawasaki disease have a signifcantly higher risk of this disease than the general population. This article reviews the onset of familial Kawasaki disease and possible pathogenesis.